PEGTA
Polyethylene (glycol) tetra acrylate is a unique tool for modulating the physical properties of a hydrogel by providing double the photoreactive groups as PEGDA1.
Basic Information
Polyethylene (glycol) tetra acrylate (PEGTA, 4-arm poly(ethylene glycol) (PEG) acryl) is a synthetic, hydrophilic starting material which forms hydrogels in the presence of photoinitiator and UV light. Like PEGDA, PEGTA hydrogels are easily customizable since ECM proteins and/or growth factors can be incorporated into a hydrogel and its stiffness can be modulated from 10-100 kPa10,11. Since PEG is its base material, PEGTA is widely recognized as a biocompatible, non-immunogenic, and capable of chemical manipulation to incorporate attachment peptides2,7, degradable peptides2,3, and other moieties4.