Glycosan hydrogels are crosslinked with acrylated polyethylene glycol (PEG) polymers. The amount of each of the crosslinkers can be changed to vary the stiffness of the resulting hydrogel1.
Glycosan offers 3 different crosslinkers to choose from depending on your application:
|PEGDA||Standard diacrylated PEG||Standard uses in 3D cell culture and Tissue engineering|
|PEGTA||Twice as many acrylates/molecule||More crosslinks and stiffer gels|
|PEGSSDA||3 internal disulfide bonds, diacrylated||Gentle cell or spheroid recovery with reducing agent after 3D cell culture|
|Stiffness Sampler Trio||No image available||3 different concentrations of PEGDA and PEGTA||Test a variety of stiffnesses|
- Vanderhooft, J. L.; Alcoutlabi, M.; Magda, J. J.; Prestwich, G. D. Rheological properties of cross-linked hyaluronan-gelatin hydrogels for tissue engineering. Macromol Biosci 2009, 9, 20-8.